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The Mancunians were able to defeat their opponent only in overtime thanks to the goal of Marcus Rushford.
Manchester United - Anderlecht 2: 1.
Goals: Mkhitaryan, 10, Rushford, 107 - Hanni, 32 Manchester United: Romero - Valencia, Bayi, Rojo (Blind, 23), Show Carrick, Pogba - Lingard (Fellaini, 60), Mkhitaryan, Rushford - Ibrahimovic (Martial, 90).
Anderlecht: Martinez - Appiah, Mbhoji, Spayich, Obradovic - Dendonker, Thielemans, Hanni (Stanciu, 24) - Chipchu (Bruno, 64), Achimpong - Theodorchik.
Yellow cards: Thielemans, Appiah.