Genetic preconditions of restless leg syndrome are found

15 September 2017, 01:49 | Health
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Scientists from the Mayo Clinic have found the first gene associated with restless leg syndrome - a neurological disorder that manifests itself in the form of discomfort in the legs and interferes with night sleep.

The syndrome develops in 5-11% of the European part of the population, and for it, according to the study, the mutation of the gene MEIS1.

The change found on the protein site is very important for its normal functioning, because scientists consider it the culprit of the disease.



At the same time, variants of the gene MEIS1 and the BTBD9 gene associated with the first do not guarantee the development of the syndrome.

For example, scientists found no changes in BTBD9, but identified in MEIS1 production of additional protein. Three family members of six who had a MEIS1 mutation complained of restless legs syndrome. But another international study did not reveal the connection between disease and changes in DNA, after analyzing the genetic data of 1000.

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