Alternative to dental implants: new teeth were first raised in the mouth, but not human

08 February 2025, 02:58 | Technologies
photo Фокус
Text Size:

For the past 20 years, scientists manipulate genes to grow human cells where it seems unrealistic. Previously, scientists have already raised human ears and skin on mice; Human buds were grown in pork stomachs, but now scientists have gone further, writes Popular Science.

Most of these experiments are carried out in order to have one day genetically modified animals can be used to create emergency organs and tissues that can be used by people who do not have access to donors. In a new study published in the magazine STEM CELLS TRANSLATIONAL MEDICINE, scientists have found that the cells of human teeth grown in the laboratory can be used to grow dental mouth.

The focus. Technology has its own Telegram channel. Subscribe so as not to miss the latest and most exciting news from the world of science!

The authors of the work, dentists from the University of Tafts, believe that the results they get can be used once to develop biological substitutes for teeth, which can be used instead of imperfect synthetic implants used today.

In the course of the study, scientists took cells from the pulp of the human tooth, and then mixed them with the cages of the enamel of the pork tooth and sowed on the " Then they were grown in vitro in a bioreactor for a week to help cells multiply. Further, the restored toothplain, partially human, and partially pork, implanted several experimental animals into the lower jaws. Several months later, scientists have observed the formation of "

In the pig’s mouth, its usual sharp, tusks similar to tusks, located next to smaller, slightly more human dentitions. It is assumed that something likely, probably, can happen in people. The authors of the study believe that such a tooth structure can be “sowed” in the fabric of the gum of a person and ultimately make it grow into a fully formed tooth.

However, the authors of the study acknowledge that this approach can be very risky. The fact is that tooth cells that continue to grow endlessly can become cancer.

Dental implants, which are usually made of titanium or titanium alloy, and then screwed into the patient's jaw bone, have become a more popular alternative to dentures in recent years.

The study of the team from the National Institute of Health show that the tendency to increase the number of dental implants will probably only continue. But even though implants are better than the absence of teeth, they are not perfect.

For example, re -chewing of displaced synthetic teeth can lead to damage to the jaw bone, and in the worst case - rejection of implants. Bacteria on implants can also cause the development of potentially dangerous infections. At the same time, natural teeth do not need to be drilled - they are attached to the jaw with ligamentous tissues, which theoretically can reduce the risk of jaw damage in the future.

During the experiment, scientists used six two-year-old mini-vinity and surgically deleted the third incisors and the first premolars. Note that the mini-svini was chosen for a reason: their lower jaws in size and anatomy are similar to human. Further, the team placed bioengineer dental structures in the openings for removal. Two and four months later, the researchers checked again and found evidence of successful teeth growth in about 50% of pigs.

Note that earlier scientists conducted an experiment with two -month animals, but the results were not so positive. It is assumed that the teeth that appeared with age probably shifted hybrid structures.



The results of the new study are promising, but are only the first step to growing natural teeth. The authors of the study note that the teeth that have grown in a mini-vine have not reached the size of a complete human tooth and, probably, will not withstand regular use. Additional studies on this topic will be required so that in the end scientists can begin experiments in public.

Previously, Focus wrote about why prehistoric people have such white and even teeth.

Based on materials: popsci.com



Add a comment
:D :lol: :-) ;-) 8) :-| :-* :oops: :sad: :cry: :o :-? :-x :eek: :zzz :P :roll: :sigh:
 Enter the correct answer