Australian Cancer researchers have successfully developed a new generation of genetic editing tool to improve the study of such dangerous human diseases. With the help of her, scientists hope to study in more detail a deadly disease and develop effective methods of its treatment, writes Medical Xpress.

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Scientists from the Olivia Trony-John Cancer Institute and their co-authors created a genetic editing model using an improved version of the CAS12A enzyme. This breakthrough allows more accurate genetic studies and brings the methods of editing genes to the real use, they said.

Genes editing as molecular scissors, allowing scientists to cut and change DNA - genetic instructions that control cell behavior and are responsible for the manifestations of many diseases and other features.

CRISPR, widely used in medical studies and this editing, usually relies on an enzyme called CAS9. Although CAS9 was the standard over the past decade, CAS12A has a key advantage: it can delete several genes simultaneously with greater accuracy. The author of the study published in the journal Nature Communications, Dr. Eddie La Mark explained: "

Having experienced a new tool on the lymphoma, the varieties of blood cancer, the team revealed genes, due to which the disease developed faster. They also combined CAS12A with other editing methods, which allowed them to make more complex changes to DNA. Scientists Wei Jin and Yexan Deng said that they also crossed the animal model CAS12A with a model expressing the changed version of CAS9, which allowed them to simultaneously delete and activate various genes. This will allow researchers to use this tool for modeling and studying complex genetic diseases, authors say.

Professor Marco Herold, one of the leading researchers, believes that this discovery will help scientists around the world. "

The ability to edit several genes can simultaneously become the basis for new methods of treating serious diseases. As genes editing are getting closer to use in real medical procedures, researchers also work on ways to safely introduce these instruments into the body of patients. Professor Gerold added: " The purpose of the authors is to verify the safety and effectiveness of this technology for future treatment methods using it.

Previously, Focus wrote why brothers and sister are not copies, contrary to established beliefs. Delassing widespread myths, the expert examined the fascinating world of genetics and unpredictable DNA, which we share with brothers and sisters.

Focus also wrote about the improvement of CRISPR genes editing technology. The new version shows that the increase in accuracy of CRISPR-CAS9 technology reduces the risk of transformation of cancer cells during genetic therapy.

Important! This article is based on the latest scientific and medical research and does not contradict it. The text is exclusively informational in nature and does not contain medical advice. To establish a diagnosis, be sure to consult a doctor.