Biologists have determined why the lungs are affected by coronavirus

08 June 2021, 18:17 | Science
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Researchers have discovered the cause of mass destruction of the lungs when infected with a new type of coronavirus infection. They argue that this involves one of the fragments of the SARS-CoV-2 envelope and the PALS1 protein, which is responsible for the adhesion of cells to each other.. The results of the work were published in the scientific journal Nature Communications. " It helps SARS-CoV-2 particles spread faster. Therefore, such a feature of a new type of coronavirus, which most likely arose by accident, should have quickly become entrenched in the genome of the ancestor of all its strains, " As a result of infection with SARS-CoV-2, lung tissue is damaged, and its cells die in large quantities. Thus, the development of a severe form of pneumonia is provoked.. Scientists suggest that the most severe consequences of COVID-19 are associated not only with viral particles, but also with disorders in the functioning of the immune system, as well as lung cells, which they themselves cause.. Experts have developed detailed three-dimensional models of SARS-CoV-2 coat proteins and found out with which cellular compounds they can interact. The experiment showed that one of the fragments of the coronavirus envelope, called Ec18, is able to integrate into the molecules of the PALS1 protein, which plays a major role in connecting lung cells to each other..

This was confirmed by further experiments, proving that the protein is incorporated into PALS1, which in this case destabilizes and affects immune cells, creating an inflammatory process. In addition, the virus spreads much faster this way.. Recall that the Ukrainian Institute of Molecular Biology and Genetics conducted successful research on the treatment of severe coronavirus pneumonia with stem cells. For six months, mortality from influenza and pneumonia in Ukraine has tripled News from Telegram. Subscribe to our channel https: // t. me / korrespondentnet Author: 1.




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