It looks like scientists have added one more to the billion reasons to quit smoking..

New study shows secondhand smoke increases risk of weight gain.

Employees of Brigham Young University in Provo (Utah, USA) spoke about this on the pages of the American Journal of Physiology: Endocrinology and Metabolism.

Today everyone knows that smoking is a great health hazard.. But before, it was mostly about cancer and chronic obstructive pulmonary disease (COPD). In the latest work, scientists touched on a painful topic for developed countries - obesity and overweight..

Medical News Today recently reported on a new study that found that non-smokers living under the same roof as smokers inhale 3 times more harmful particles than the WHO guidelines..

According to the authors of the latest study, half of the US population inhales someone else's tobacco smoke at least once a day, and about 20% of young children in the country live near smokers.. Professor Benjamin Bikman warns: “People who have a smoker in the house, especially children, have the problem of an increased risk of cardiovascular and metabolic diseases.”.

Every day in America of 330 million, about 4,000 young people smoke their first cigarette, and 1,000 people become regular smokers..

Smoking disrupts mechanisms related to cell response to insulin.

Professor Beekman and his university colleague Paul Reynolds (Paul Reynolds) were interested in how cigarette smoke affects metabolism. In particular, they wanted to understand why smokers are more likely to develop insulin resistance than others..

They did an animal study using mice that were forced to breathe cigarette smoke regularly.. The scientists then studied the metabolic profile of the rodents using the latest laboratory techniques.. It was found that smoking mice gain more weight, and at the cellular level, tobacco toxins caused changes in mitochondria via the lipid ceramide.. This led to a disruption in the response to insulin and the normal functioning of cells..

Commenting on the results of the study, Reynolds said: " If a person becomes resistant to insulin, their body requires more of this hormone.. This mechanism is responsible for the deposition of excess weight..

Based on this, the scientists suggested that the effect of cigarette smoke could be reversed by inhibiting (suppressing) the activity of ceramide..

When scientists tried to treat mice with myriocin, a ceramide blocker, they did not observe the weight gain and metabolic disturbances that are characteristic of “smoking” rodents..

Interestingly, when mice treated with myriocin were given a sugar-rich diet, even the drug did not save them from metabolic disorders..

The team is now preparing to study the safety of a ceramide inhibitor in humans.. Professor Beekman says: "

By the way, the other day, American scientists accused smoking that it violates pain sensitivity and increases the risk of lumbodynia - chronic back pain..

medbe. en.