Immunosuppressor may help combat periodontal disease

01 May 2020, 22:26 | Health
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Scientists have found that a drug that prolongs the life of mice has helped to eliminate their age-related dental problems.. We are talking about the immunosuppressant Rapamycin, which is currently used to prevent organ rejection in recipients..

“We suggested that biological aging contributes to the development of periodontal disease, and that interfering with the aging process can also delay the development of the disease,” says lead author Jonathan An of Washington University.

An and colleagues added the drug to the food of middle-aged mice for eight weeks and compared the state of their oral cavity with mice that were not exposed to the drug..



Using microcomputer tomography, the group examined periodontal bone in mice.. The results showed that in animals that used the drug, bone mass was greater than in the control group. During the period of getting Rapamycin, they managed to grow a new bone.. In addition, scientists noted a decrease in gum disease..

Researchers emphasize that clinical trials in humans are required since Rapamycin has certain side effects..

https: // www. medikforum. com /.

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