The remedy for dementia has worked on mice

08 September 2017, 00:44 | Health
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Researchers from the United States found a fundamentally new drug for the treatment of Alzheimer's, reports Science Daily. The results of the work of scientists from the University of California in Irvine (UC Irvine), led by Professor Andrea Tenner (Andrea Tenner) published in the Journal of Immunology.

In the brain of people suffering from Alzheimer's disease, deposits of amyloid protein are formed, which lead to a violation of the transmission of nerve impulses. In places where these deposits form, inflammation begins, immune cells accumulate, which causes additional damage to the neurons and aggravates the course of the disease, according to the Internet publication for girls and women aged 14 to 35 Pannochka. net The experimental drug PMX205 prevents the accumulation of cells of the immune system at the sites of formation of amyloid plaques.

Within 12 weeks, scientists gave the drug to genetically modified mice suffering from Alzheimer's disease. Then the researchers conducted tests to determine the intellectual functions (training, memory) of experimental animals.

It turned out that the mice that received the PMX205, according to the test results, did not differ much from healthy individuals. The memory and training of animals that were not given a drug, on the contrary, worsened significantly.

In addition, in the brain of the treated mice, scientists found half the amount of amyloid deposits, compared to animals that did not receive the drug.

PMX205 is the first substance that reduces the amount of amyloid formations in the brain of those suffering from Alzheimer's disease. According to Andrei Tanner, the best medicine will work in combination with drugs that eliminate other manifestations of the disease.

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Based on materials: pannochka.net



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