Experiments conducted in mice indicate that life expectancy can be associated with mother's nutrition during pregnancy, according to scientists from Cambridge University. It turns out that a balanced diet during pregnancy - a longer life expectancy and better health of the offspring, and with insufficient nutrition - premature death, according to the Internet edition for girls and women from 14 to 35 years old Pannochka. Net Direct results can not be directly applied to humans, but since the late 1980s it became known that children born with a small weight are more prone to heart disease and hypertension in adulthood. "Intrauterine growth significantly affects the number of days allocated," say physiologists from Oregon Health Sciences University.
Not all specialists agree with this assumption. Thus, scientists from the Institute for International Health, Sydney believe that "even if the mother's diet influences life expectancy, compared to the contribution of environmental factors, it is very small".
On models with mice, low or high protein diets were used. Progeny, obtained from "starving mothers", fed mice that were on an enriched diet, and vice versa, having in utero enough food of mice nursed their milk animals with a limited diet. This was done in order to level the chances and create the same growth conditions. As a control mouse with normal nutrition, both in the intrauterine period, and after. In average, mice live about 2 years. Those whose mothers were well fed, lived 2 months longer. Progeny from undernourished mothers died 6 months earlier than control.
At the second stage of the study, half the offspring were transferred to a 21-day high-calorie diet, with a lot of sugar similar to that which leads to obesity in humans. The second half on a standard diet. The life expectancy of offspring from mothers with poor diet, transferred to an over-nutrition diet, was 1 year, that is, 2 times less control.
In offspring from mothers with increased nourishment, an episodic high-calorie diet did not affect the life expectancy of animals as a whole who maintained a moderate diet.
It is assumed that the previously deprived of food animals increased appetite, in order to catch up. With insufficient intrauterine nutrition, the kidneys are most often affected. "Is it possible that these once-occurring differences are amplified within 7 to 8 decades of the man's assigned time? ", The authors suggest.
Medicus. En.