American virologists from the University of Thomas Jefferson have developed a new tool for rabies vaccination, which at an early stage prevents the further development of the disease, according to an online edition for girls and women from 14 to 35 years old Pannochka. Net Currently, people are using vaccines based on inactivated rabies virus to prevent rabies. To create a new drug, scientists used live attenuated pathogens. The results of the experiment were published in the journal Nature.

The researchers included in the genetic code of the virus three copies of the gene that encodes the surface protein, which causes an immune reaction in the human body. In addition, virologists replaced two amino acids in this protein. Due to these changes, the damaging effect of protein on the body was avoided, and the strength and speed of development of the immune response to infection increased.

Scientists conducted experiments in mice in which the vaccine confirmed its safety (introduction of the drug into the brain of healthy young individuals did not cause them a disease) and effectiveness (the introduction of the vaccine within three days after infection prevented the development of rabies in experimental animals). In addition, within three weeks after the introduction of the vaccine, the mice showed resistance to infection, which indicates the possibility of using this vaccine for the prevention of rabies, experts say.

Medicinform. Net.