For the first time in humans, asymptomatic "quiet" seizures that were found in mice with Alzheimer's disease a decade ago. The discovery potentially shows new opportunities for treating a disease that affects about one in ten people over the age of 65, writes Ortodox,. A team of neuroscientists led by Jeffrey Noble of the Baylor College of Medicine in Texas informs in Nature Medicine that seizures in the depth of the hippocampus were recorded in two patients with Alzheimer's disease who volunteered to put probes into their brains. Since scientists discovered "quiet" seizures in mice, it was thought that such electrical discharges occur in the human brain affected by Alzheimer's disease. However, collecting evidence was not an easy task. Such cramps often remain unnoticed by patients or doctors.
Although epilepsy is often present in people with Alzheimer's disease, it is usually absent in most patients who have a "sporadic" or unrelated variant of the disease. "It's very interesting that we were able to move from observation in genetically modified mouse models of Alzheimer's disease to demonstrating the same phenomenon in patients with verified Alzheimer's disease," says Noble.
Original article: Scientists have made a new discovery in Alzheimer's disease.