Scientists have created the world's first "

04 August 2022, 14:00 | Technologies
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Scientists from the Weizmann Institute in Israel were the first in the world to create " At the same time, the researchers did not need sperm, eggs and the fertilization process, reports The Guardian..

Experts have found that mouse stem cells can themselves assemble into structures similar to embryos. At the same time, they have an intestinal tract, the rudiments of the brain and a beating heart..

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The structures created by scientists are called " They will help scientists better understand how tissues and organs are formed during the natural development of embryos..

The scientists also hope their work will reduce the number of animal experiments and ultimately pave the way for new sources of cells and tissues for human transplantation.. For example, skin cells from a leukemia patient could potentially be converted into bone marrow stem cells to treat their condition..

“Remarkably, we show that embryonic stem cells generate whole synthetic embryos, including the placenta and yolk sac surrounding the embryo,” said study lead author Professor Jacob Hanna..

Last year, the same team of scientists was able to create an artificial womb, inside which natural mouse embryos could grow for several days.. In the new work, the same device was used to grow stem cells for a week, which is about half the gestation period of a mouse..

Some cells were pre-treated with chemicals that included genetic programs to develop into the placenta or yolk sac, while others developed without interfering with organs and other tissues..

Most stem cells failed to form embryos. But 0.5% formed small balls, from which individual tissues and organs grew.. Synthetic embryos are 95% identical to natural ones in terms of internal structure and genetic profiles of cells.

Scientists also believe that the formed organs were functional.

But Hanna emphasized that the synthetic embryos were not " The scientist founded a company called Renewal Bio, whose goal is to grow synthetic human embryos to obtain tissues and cells for the treatment of diseases..

At the same time, scientists who were not involved in the study believe that it is already necessary to determine the framework within which such activities will be regulated before such companies are launched..




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