American scientists have successfully tested HIV vaccine

10 December 2021, 07:50 | Science
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In the United States, biologists have developed a messenger RNA vaccine for HIV and have successfully tested it in mice and rhesus monkeys. This was announced on Thursday, December 9, by the chief infectious disease specialist of the United States and director of the National Institute of Allergy and Infectious Diseases (NIAID) Anthony Fauci.

According to him, the new drug consists of special fat nanoparticles that encode part of the proteins of the immunodeficiency virus.. They can penetrate human cells and force them to produce a large number of fragments of the HIV protein coat, thus forming an immune response to the virus..

Fauci clarified that scientists prepared RNA chains that forced cells to produce two viral proteins at once - the env protein, which forms the basis of the HIV envelope, and the gag protein, which plays the role of the internal scaffold of viral particles.. These chains were embedded in fat particles that are most similar in characteristics to a real immunodeficiency virus.

According to the results of the experiment, a vaccine that attacked both viral proteins reduced the risk of HIV infection by about 79%. If it was injected several times, the level of protection against the virus was increased without causing dangerous side effects..

Biologists plan to improve new HIV vaccine to reduce the number of injections needed. After that, in the coming years, the drug will be tested in humans..

As reported, in Japan, scientists cured a monkey of HIV. The vaccinated animal was infected with the immunodeficiency virus, and its body overcame the disease.

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