The use of medications is one of the main components of the treatment of osteochondrosis. Non-steroidal anti-inflammatory drugs for osteochondrosis do not affect the mechanism of the development of the disease, but they can stop pain and reduce inflammation.. Such drugs can be used in the form of tablets, injections, gels and ointments..

Non-steroidal anti-inflammatory drugs are not able to eliminate osteochondrosis, they are used to relieve pain Non-steroidal anti-inflammatory drugs for the treatment of osteochondrosis: how they work Pain syndrome is the main symptom of spinal osteochondrosis at any stage. Non-steroidal anti-inflammatory drugs (NSAIDs, non-steroidal anti-inflammatory drugs, NSAIDs) are used to reduce pain.

The mechanism of action of NSAIDs is associated with the suppression of the enzyme cyclooxygenase (COX), which is involved in the formation of prostaglandins - pro-inflammatory mediators.. There are two types of cyclooxygenase present in the human body:.

COX-1 - " Stays in the body all the time. Responsible for gastric mucus production, platelet function and renal blood flow.

COX-2 - " Normally absent, begins to function only with inflammation.

Depending on what type of COX blocks the drug, there are several groups of NSAIDs - non-selective and selective.. Representatives of the first group inhibit both COX-2 and COX-1, which often leads to damage to the gastric mucosa and the development of other adverse reactions.. Selective NSAIDs are a new generation of drugs, they block only COX-2, which activates inflammation and pain.. In this regard, adverse reactions with the use of this group of drugs occur less frequently..

Indications and contraindications NSAIDs, like other medicines, should be prescribed by a doctor if indicated. Before using them, you need to carefully study the list of contraindications and make sure that they are absent..

When NSAIDs are indicated The main indication for the use of these drugs for osteochondrosis is the presence of pain syndrome. NSAIDs can be used regardless of the stage of osteochondrosis and the presence of other symptoms..

Contraindications It is not recommended to use drugs from the NSAID group in the following conditions:.

Erosive and ulcerative diseases of the gastrointestinal tract - erosive gastritis, peptic ulcer of the stomach and duodenum. If necessary, preference should be given to selective NSAIDs.

High risk of developing cardiovascular diseases - atherosclerosis, bleeding disorders. If necessary, preference should be given to non-selective NSAIDs (Ibuprofen, Naproxen).

Liver and kidney diseases in the stage of decompensation.

Systemic agents For the treatment of osteochondrosis, systemic drugs are more often used - intramuscular, intravenous injections and tablets. Systemic drugs more effectively eliminate pain and inflammation, as they enter the general bloodstream. Their disadvantage is the more frequent development of side effects..

Tablets Oral NSAIDs are often given. Their action occurs more slowly than with injection - after 20-30 minutes. But oral administration also has a number of advantages:.

can be taken at home;

non-invasive method;

no local complications (hematomas, infection).

Tablets that are used to relieve pain can be classified as selective and non-selective NSAIDs, and also have a different severity of analgesic effect..

Ibuprofen - a drug from the group of NSAIDs of non-selective actionNSAID group.

Drug names.

Non-selective.

List of NSAIDs (from drugs with the most pronounced analgesic effect to weaker ones):.

Ketorolac (Ketalgin, Ketanov);

Diclofenac (Diklak, Dicloberl);

Indomethacin (Metindol);

Ibuprofen (Ibuprom).

selective.

Celecoxib (Celebrex);

Meloxicam (Movalis);

Etodolak (Etol fort).

InjectionsInjections (intramuscular, intravenous) can be used to treat osteochondrosis. Their advantage is a faster action, as they immediately enter the bloodstream.. With intravenous administration, the action begins after 2-4 minutes, with intramuscular injection - after 5-10 minutes.

Parenteral administration of drugs has a number of disadvantages:.

Difficulty in use - in most cases, injections are not done at home.

Invasiveness - there is a possibility of infection, vascular damage and hematoma formation.

Drugs that are available in the form of ampoules for injection are also divided into selective and non-selective NSAIDs.. The most common NSAIDs include:.

Ketorolac (Ketalgin, Ketanov);

Diclofenac (Diklak, Dicloberl);

Meloxicam (Movalis);

For severe pain, diclofenac is given as an injection. They act weaker, but at the same time practically do not cause side reactions..

List of local NSAIDs:.

Active substance.

Names of medicines.

Diclofenac.

Voltaren emulgel;

Diclac gel;

Diclogen gel;

Diclomec gel;

Doloxen gel;

Clodifen gel.

Indomethacin.

Indomethacin;

Indomethacin Sopharma ointment;

Indomethacin-Acri;

· Indovazin.

Nimesulide.

Nise gel.

Ibuprofen.

Long gel;

Dolgit cream;

Ibalgin cream;

Nortafen;

Nurofen.

Ketoprofen.

Artrokol;

Valusal;

Ketonal;

Ketoprom;

· Ketum-gel.

Artrocol gel contains ketroprofen as an active ingredient. Damage to the stomach and intestines is associated with the suppression of COX-1, which is responsible for the production of mucus and protection of the lining of the digestive tract. The most common gastrointestinal manifestations include:.

abdominal pain;

nausea, vomiting;

diarrhea;

gastrointestinal bleeding.

The likelihood of damage to the gastrointestinal tract depends not only on the choice of drug (selective, non-selective COX inhibitor), but also on the dose and duration of use. The higher the dose, the longer the drug is used - the higher the likelihood of ulceration of the mucous membrane.

Adverse reactions from the cardiovascular system and kidneys may also develop.. Selective NSAIDs affect the function of the vascular endothelium and the blood coagulation system. As a result, the risk of myocardial infarction and stroke may be increased.. Long-term use of NSAIDs is also associated with the formation of analgesic nephropathy..

How to choose a medicine Not all representatives of NSAIDs are equally good, they differ in the following characteristics:.

group - selective or non-selective;

release form - ampoules for injections, tablets, ointments;

the severity of the anti-inflammatory action;

the severity of the analgesic effect.

As a rule, when choosing an NSAID, the doctor takes into account several points: the presence of concomitant pathology, the stage of the disease and the severity of pain.

In the presence of diseases from the gastrointestinal tract, preference is given to selective NSAIDs Meloxicam, Celecoxib), since they do not suppress COX-1 and do not damage the gastric mucosa. At high risk of cardiovascular disease - Ibuprofen or Naproxen.

At an early stage of the disease, when pain is not severe, NSAIDs with a weak or moderate analgesic effect (for example, Ibuprofen) are used.. You can also use medications in the form of gels and ointments..

If the pain is severe, drugs with a pronounced analgesic effect are taken (Ketoprofen, Ketorolac).

Is it possible to cure osteochondrosis with NSAIDs It is not recommended to limit treatment to only one group of medicines.

The use of NSAIDs is usually combined with other drugs and non-drug treatments:.

chondroprotectors;

centrally acting muscle relaxants;

B vitamins;

physiotherapy;

physiotherapy;

massage and manual therapy;

spinal traction.

The use of NSAIDs refers to the symptomatic treatment of osteochondrosis. That is, funds from this group do not cure the disease, but only fight its symptoms..

neboleem. net.