American researchers recently conducted an experiment involving the replacement of an entire Y chromosome with just two genes in infertile male mice, after which the animals produced normal offspring, according to Pannochka, an online publication for girls and women from 14 to 35 years old.. net As you know, the sex Y-chromosome, present exclusively in males, contains the Sry gene, which triggers the mechanism for the development of a living organism according to the male type. The chromosome also contains the genes necessary for the production of spermatozoa.. Modern technologies make it possible to use even immature sperm for fertilization, but researcher Yasuhiro Yamauchi from the University of Hawaii demonstrated in his work that even a whole Y chromosome is not necessary for procreation..

A research team has created mice in the lab with only two Y genes: Sry and Eif2s3y, which controls sperm production.. The test animals, in fact, should have been born sterile. Having fertilized immature eggs with them, scientists transplanted them into the body of surrogate females..

As a result, offspring appeared that were quite viable, but their ability to reproduce was worse than that of their normal relatives..

Scientists decided to go further by replacing the Sry gene with three other Y genes, then the ability of mice to reproduce offspring increased..

This discovery, as the authors believe, will help create a technology in the future that will allow infertile men to have children, since, as the experiment showed, it is enough to use the Sry and Eif2s3y genes for this..

global science. en.