Loss of smell in Covid is associated with genetic disorders: scientists told how they will treat it

07 September 2022, 21:22 | Health
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Loss of smell in Covid is associated with genetic disorders: scientists told how they will treat it. And the reason is in violations at the genetic level..

Why the sense of smell disappears with coronavirus Of course, if - just like with a common cold - the nasal mucosa just clogs up, then this is a short-term phenomenon, with recovery it disappears. True covid anosmia is when the ability to smell does not return for many weeks, months. Doctors do not exclude the loss of smell due to the coronavirus forever, in their opinion, it can be so if the neurons die under the influence of the pathogen. The cells of the central nervous system are practically not restored.

Recently, scientists from Canada decided to analyze what exactly happens when the neurons are alive and the nose breathes, but there are still no smells.. As they explained, in this situation we are talking about violations in the work of the olfactory bulb and olfactory nerve.. Odor signaling is degraded there. And, according to published data, this is due to genetic failures..

How covid anosmia can be treated Researchers have created a list of more than 50 genes that affect the sense of smell. Accordingly, changes in them can lead to anosmia.. Among them, six of the most “influential” were chosen. According to scientists, in theory, all of them can be brought back to normal by the action of certain molecules that will attach to these genes and correct their activity.. Moreover, some of these molecules are present in existing drugs..

For example, drugs that target two of these six DNA regions are currently in the testing phase.. Geneticists suggest that a drug previously approved for the treatment of pancreatitis is suitable for correcting the NRP1 gene. In their opinion, its molecules will successfully attach to this gene.. And at the same time they will help to establish the work of another one, because it is connected with NRP1.

Recall that in September 2022, lockdown is again introduced in China due to the outbreak of Covid-19.

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