How to fool the flu virus

08 July 2022, 14:51 | Health
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Antibodies against the PD-1 protein of programmed cell death receptors T-cells will help fight the flu, according to Pannochka, an online publication for girls and women aged 14 to 35. net Reported by Dr. Emilio Flano of the National Children's Hospital in Columbus, Ohio..

Some viruses, including the influenza virus, use this receptor to deal with the host's immune system..

By blocking PD-1, it is possible to prevent the virus from suppressing the T-cell response.



In a mouse study, intranasal administration of antibodies against PD-1 was shown to reduce the viral load in rodents within 3 days of illness onset.. After 5 days, the level of viral load is not recorded at all.

Similar results have been obtained in cultured human cells.. You can read more about this interesting work in the Journal of Virology..

Despite the optimistic results, the scientists noted that previous attempts to inhibit PD-1 ligands have been ineffective in treating HIV, hepatitis, and other chronic viral infections in humans..

medbe. en.

Based on materials: pannochka.net



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