The effect of a combination of magnesium, vitamins B6, B9, B12, rhodiola and green tea on stress was evaluated in chronically stressed people who do not have other diseases, writes Nutrients.

The effect on stress-related quality of life parameters (sleep and pain perception) has also been studied.. Adults with stress during? 1 month, scored? 14 points on the Depression and Anxiety Scale (DASS)-42 questionnaire, were randomized (1:1) to oral Mg-theadiols (n \u003d 49) or placebo (n \u003d 51), for 28 days, followed by a score of 56.

The primary endpoint was change from baseline in DASS-42 stress score on day 28 of Mg-theadiola versus placebo.. DASS-42 stress scores decreased significantly from baseline by day 28 of Mg-Theadiola compared to placebo (effect size 0.29; 95% CI [0.01, 0.57]; p \u003d 0.04). Similar contractions were observed on day 14 (p \u003d 0.006) and day 56 (p \u003d 0.02).

There was a significant decrease in sensitivity to cold pain (p \u003d 0.01) and a trend towards a decrease in sensitivity to warm pain (p \u003d 0.06) on day 28.

“Improvement in daytime dysfunction due to sleepiness (Pittsburgh Sleep Quality Index-7 component score) was reported at day 28 and was significant at day 56 (p \u003c 0.001). Mg-Theadiol is effective in managing stress in healthy individuals. Its beneficial effects on sleep and pain perception require further study,” the study reports..

medical-heal. en.