Blood cancer is characterized by pathological disorders that cause uncontrolled hematological cell division.. A group of scientists have determined that carotenoids can effectively help in the fight against this disease..

Researchers have explored various blood cancer treatment strategies, including chemotherapy, Car-T therapy, chimeric antigen receptor targeting, and platelet therapy.. However, all of these treatments pose serious problems that limit their use in blood cancer therapy, such as poor metabolism.. In addition, the solubility and stability of anticancer drugs limit efficacy and biodistribution and cause toxicity.. Isolation and purification of natural killer cells during Car-T cell therapy is a major challenge.. To address these issues, treatment strategies with phytomedical scaffolds have been evaluated for the treatment of blood cancer, reports Nutrients..

One of the ways to treat blood cancer, scientists call the use of carotenoids. The group of carotenoids is made up of foods, as well as supplements consisting of carotene (vitamin A). These compounds, due to their antioxidant properties, are quite important substances in the prevention of many oncological diseases, as well as the prevention of relapses in patients undergoing surgical treatment for the removal of a malignant tumor..

Thanks to the protective properties of carotene, brain cells are protected from the damaging effects of free radicals.. Scientists also call lutein and zeaxanthin important carotenoids for the human body - they have a protective effect on our eyes, preventing the development of cataracts, as well as reducing the risk of macular degeneration, which causes vision loss..

An equally important carotenoid is lycopene, thanks to which it is possible to reduce oxidation processes, as well as the accumulation of cholesterol plaques on the walls of blood vessels.. One of the important properties of this compound is its ability to prevent the development of breast, endometrial and prostate cancer.. Well, the leaders in the content of this compound are undoubtedly tomatoes..

Carotenoids are a versatile class of phytochemicals that have therapeutic efficacy in the treatment of cancer, particularly blood cancer..

Carotenoids, through various signaling pathways and mechanisms such as AMPK activation, expression of biochemical markers of autophagy (p62/LC3-II), activation of the Keap1-Nrf2/EpRE/ARE signaling pathway, nuclear factor kappa light chain enhancer of activated B cells (NF.

“This review article focuses on the therapeutic potential of carotenoids in blood cancer, looking at the various mechanisms and signaling pathways that mediate their therapeutic efficacy,” the study reported..

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