Previous studies have already shown a link between depression and diabetes, but scientists were not sure about the mechanism that underlies this link, according to Pannochka, an online publication for girls and women aged 14 to 35.. net In 2010, researchers at the Harvard School of Public Health in Boston, who were studying the relationship between depression and diabetes, analyzed a large group of 65,381 women. The team found that not only were women with diabetes at high risk of depression, but women with depression were also more likely to develop diabetes..

The authors of this study found that women with depression develop diabetes mellitus 17% more often, and if patients also take antidepressants, then 25% more often compared to those who do not have depression..

On the other hand, women with diabetes have a 29% greater risk of depression, and those who take insulin have a 53% greater risk of depression compared to participants without diabetes..

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This scientific work gave impetus to a new study, which was jointly organized by Dr. Nicholas Bolo (Nicolas Bolo) from Beth Israel Medical Center and Dr. Donald Simonson (Donald Simonson) from Brigham Women's Hospital in Boston.

The biochemical link between diabetes and depression.

“Traditionally it has been thought that patients with type 1 or type 2 diabetes have a higher risk of depression due to the high levels of stress they experience while dealing with a complex chronic disease on a daily basis.. Our results suggest that high blood glucose itself predisposes patients with type 1 diabetes to develop depressive states caused by biochemical changes in the brain,” write Bolo and Simonson..

The researchers studied a small group of 3 men and 5 women (mean age 26 years) with type 1 diabetes compared to a control group of 6 men and 5 women (mean age 29 years). None of the participants met the criteria for clinical depression.

Using functional magnetic resonance imaging, scientists assessed the level of glutamate, a neurotransmitter that is associated with depression in humans.. Participants' brains were scanned at both normal sugar levels (90-110 mg/dL) and moderately elevated levels (180-200 mg/dL).

The authors concluded that when sugar levels rise, the connection between brain areas that are responsible for self-perception and emotions weakens, so patients with diabetes become more prone to depression..

An increase in glucose levels was also associated with an increase in glutamate in patients with diabetes, but not in healthy participants.. High Brain Glutamate Correlates With Poor Depression Severity Chart Scores.

Dr. Bolo believes that the results "

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