The drug for covid only helps men The steroid drug dexamethasone, which is actively used in severe COVID-19, is only beneficial for men. This is the conclusion reached by researchers from Canada.

Blood tests of patients with and without COVID-19 who were admitted to various departments of hospitals in Calgary, Canada with severe respiratory distress have shown surprisingly selective effects of dexamethasone.. This steroid-based drug was one of the first drugs with so-called proven efficacy, that is, helping in the treatment of coronavirus.. Humanity did not have time to create new specific drugs to combat COVID-19, and in the first months of the pandemic, those drugs that had long been synthesized to fight other diseases were tested.. The maximum effect was demonstrated by dexamethasone.

However, if in the course of clinical trials this drug helped many patients, then later in a hospital setting its effectiveness turned out to be much less outstanding.. And now it has been established that he helps men much more than women.. The number of representatives of the stronger sex dying from a severe form of coronavirus in hospitals was reduced by this drug, but it did not affect similar numbers among women..

This is due to the selective effect of interferon proteins, which help to rid the body of viruses faster.. In COVID-19, the interferon response increases, which increases the level of inflammation and more severe organ damage. Men have an exaggerated neutrophil response to interferon, and when they receive dexamethasone, this response is reduced. And in women, their neutrophilic interferon response is much more restrained.. And with dexamethasone therapy, no significant effect is noted.

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