Caffeic acid is an organic substance found in all plants, including vegetables, fruits, herbs, coffee beans, spices.
Possesses pronounced anti-inflammatory and antioxidant properties, thanks to which it was sent to the subject of medical research, according to Pannochka, an Internet publication for girls and women from 14 to 35 years old.. net Caffeic acid belongs to the group of so-called hydroxycinnamic acids, and these are combined into an even larger chemical group - polyphenols. Like other polyphenols, caffeic acid is an antioxidant: it is able to counteract oxidative stress and protect cells from free radical damage.
Oxidative stress is an important factor in cellular aging, metabolic disorders, cardiovascular and neurodegenerative diseases, and malignant tumors.
Fast facts on caffeic acid:.
• Food supplements with caffeic acid are recommended as an antioxidant.
• Many manufacturers add this substance to their face and body care products.
• Most studies have confirmed that caffeic acid is anti-inflammatory and safe in relatively high doses. Biological and health benefits of acid.
There are several main uses for caffeic acid in medicine:.
Caffeic acid treatment for cancer.
Preliminary results from in vitro studies show caffeic acid slows down the development of malignant cells and may prevent cancer.
In 2015, scientists analyzed the results of taking this antioxidant in a cohort of 1,090 breast cancer patients.. It was found that taking caffeic acid is associated with a slowdown in tumor growth and a decrease in the likelihood of metastasis in estrogen-positive breast cancer (in combination with standard therapy).
In addition, a 2014 study demonstrated the inhibition of colon tumor cell growth, both in vitro and in animal models..
Other studies, however, produce mixed results..
In 1988, scientists looked at the effects of caffeic acid on malignant tumors in mice.. Although the antioxidant did slow down tumor growth, it turned out to be less effective than its direct rivals, chlorogenic and ferulic acids..
A 2000 study examined the effects of caffeic acid on oral tumor cells. The drug turned out to be quite effective and completely harmless to healthy cells.. These experiments were carried out only in vitro, with cell cultures. It remains to be seen how the drug will act in real conditions, in people with oral cancer..
In 2003, the possibility of using caffeic acid for the treatment of breast cancer was once again considered.. Then it was possible to confirm that the molecule of this antioxidant is capable of "
To summarize the evidence, caffeic acid is a viable option when it comes to cancer treatment..
But it has not been proven to replace standard methods, so patients should not consider caffeic acid as a substitute for chemotherapy or surgery.!
The fact that caffeic acid does not harm healthy cells may indicate the safety and possibility of long-term use of this supplement after consulting a doctor..
But do not forget that the results of experiments with animals cannot always be transferred to humans.. Research on the anticancer potential of caffeic acid continues.
Chronic inflammation.
The anti-inflammatory effects of caffeic acid have been the focus of researchers since the 1990s.. It has been found that this organic acid can directly bind inflammatory mediators, opening a vicious circle. Rheumatoid arthritis and autoimmune diseases, atherosclerosis and diabetes mellitus - the possibilities are endless.
Diabetes treatment.
Experiments on mice have shown: caffeic acid successfully fights some of the consequences of diabetes. So, in 2009, it was found that this substance stimulates the production of insulin by the beta cells of the pancreas in rodents with type II diabetes mellitus.. The effect is complemented by the anti-inflammatory properties of the drug.
Prevention of thrombosis.
Caffeic acid significantly reduces the risk of blood clots and lowers blood triglycerides in both animals and people with atherosclerosis.
Deceleration of aging.
Like other antioxidants, caffeic acid can slow down the physical aging process. In theory, it should maintain the elasticity of the skin, prevent the appearance of wrinkles and other signs of aging..
Doses and side effects of caffeic acid.
Scientists tested different doses of caffeic acid on volunteers, sometimes combining it with other herbal substances to increase its effectiveness.. In general, caffeic acid is well tolerated and does not cause serious side effects, even at doses well above the manufacturer's recommended dosages..
Unfortunately, today in no country there are officially approved indications, doses and specific regimens for taking caffeic acid for certain diseases..
The maximum tolerated doses of this substance have also not been established..
Can i get enough caffeic acid from food
Since caffeic acid is present in most plant foods, you will not be deficient in this nutrient with a varied diet.. Food allergy to caffeic acid is extremely unlikely. But before you start taking, as with other dietary supplements, it is advisable to consult a doctor.
Food Sources of Caffeic Acid.
A key source of this antioxidant is regular ground coffee..
Other valuable products include:.
• Beer.
• Berries.
• Dried fruits.
• Seed oil.
• Sage.
• Thyme.
• Oregano.
• Peppermint.
• Nutmeg.
• Cinnamon.
• Cumin.
• Sunflower.
• Olives Caffeic acid should never be considered a substitute for standard treatments for cancer, atherosclerosis, angina pectoris, diabetes and other diseases.!
Even the most recent research does not prove that she alone can cure any particular disease..
medbe. ru.