A few words about the so-called " The problem of cancer pathogenesis, thanks to the efforts of experimental oncology, can be considered largely resolved.. Experimental pathology data, on the one hand, established the certainty of the existence of a predisposition to cancer.. On the other hand, the same data force to attribute cancer in a number of cases of its occurrence to the field of occupational and domestic diseases.. Experiments in the reproduction of experimental cancer by systematic, prolonged, moderate strength of irritation by chemical and physical agents can be considered successful.. At the same time, these experiments are direct proof of the correctness of the above proposition..

If, as it was clarified in the previous chapter, the pathological state of the mesenchyme underlies the predisposition to cancer, the basis of the cancerous constitution, then, on the other hand, it is the mesenchyme that is the conductor from the external environment into the body of those influences of occupational and everyday conditions that contribute to. These influences, as experimental, so-called tar cancers show, act in two directions, causing irritative proliferation of the epithelium and inhibition of the resistance of the elements of the reticuloendothelial system.. The latter condition is absolutely necessary for the development of the tumor..

It would be possible to significantly lengthen a number of examples showing the undoubted influence of the environment of life on the constitution of the organism.. It seems to us that this is no longer necessary.. We have seen how important the environment of life is for the development of states of immunity and allergies, for creating a predisposition to malignant tumors, for the emergence of pathological types of metabolism, for the formation of types of normal and pathological constitution..

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