Lipomatosis is a tumor-like growth of adipose tissue, which manifests itself as multiple nodes in the subcutaneous base, intermuscular tissue, according to Pannochka, an Internet publication for girls and women from 14 to 35 years old. net Lipomas, or wen, are benign, limited growths of adipose tissue in the form of yellowish nodes with a greasy sheen, developing in a loose subcutaneous layer of connective tissue. Lipoma substrate is white adipose tissue. The structure of the lipoma is identical to the structure of mature adipose tissue: it has a lobular structure, each of the lobules consists of specialized cells with high cellular activity - adipocytes, large single-droplet fat cells with clear contours. In addition, the lipoma contains a certain amount of connective tissue that forms its capsule.. Multiple occurrence of lipomas is referred to as lipomatosis.

The prognosis for life with lipomatosis is favorable, due to the slow development and benign course of the pathological process.

Causes of lipomatosis The etiology of lipomatosis has not been established.. It is assumed that the disease is associated with the following factors:.

hereditary predisposition;

hypofunction of the thyroid gland and pituitary gland;

endocrine dysfunction;

pathologies of the liver, kidneys, pancreas, gastrointestinal tract;

impaired glucose absorption;

violation of the mechanism of reverse regulation of fat formation;

intoxication factors;

hypodynamia;

alcoholism.

Forms.

According to the distribution, lipomatosis is classified into general and local (local).

Depending on the nature of the process, the following forms are distinguished:.

diffuse lipomatosis - characterized by the presence of diffuse growths of adipose tissue without clear boundaries in the subcutaneous tissue, interlayers of connective tissue, parenchyma of some organs;

nodular - differs in the formation of painful, dense, clearly limited from the surrounding subcutaneous fatty tissue fatty nodes;

diffuse nodular - mixed form.

There are also special forms of lipomatosis, which are determined by the characteristic superficial localization:.

hypertrophic (pseudo-athletic) lipomatosis - multiple lipomas in the shoulder girdle;

Roche-Leri syndrome - lipomas concentrate on the trunk and limbs (below the level of the nipples and above the knee joints);

Madelung lipomatosis - multiple symmetric lipomatosis, lipomas are localized in the neck in the form of a clamp;

Verney lipomatosis - Potena - multiple lipomas in the supraclavicular areas;

Pasteur's lipomatosis - lipomas are placed on the lateral surface of the chest;

Derkum disease (\;

palmar lipomatosis.

Symptoms of lipomatosis Symptoms are varied and depend on the form of lipomatosis.

Slowing down the progression of the pathological process will help adherence to a therapeutic diet aimed at normalizing fat metabolism.

Dercum's disease - the development in the subcutaneous tissue of multiple, often symmetrical lipomas or diffusely localized fatty formations that show pain.

Dercum disease symptoms:.

the appearance of pathological fatty deposits on the body and extremities, with the exception of the hands and feet;

pain in different parts of the body;

itchy skin;

weakness;

muscle weakness, asthenia;

reactive depressions, hypochondria.

The disease is characterized by a chronic course with periodic exacerbations. Elderly women are more likely to get sick.

One of the variants of Dercum's disease is Gram's syndrome. The disease is characterized by a combination of obesity with deforming arthrosis of the knee joints and keratoderma..

Madelung's syndrome is characterized by excessive overgrowth of adipose tissue in the neck and upper third of the trunk.. Fatty growths fill the interscapular region, spread into the supraclavicular space, forming an annular (diffuse) lipoma of the neck. With significant growth of adipose tissue, the larynx, nerve trunks, blood vessels, pharynx can be compressed. Mostly men 35-40 years old are ill.

Symptoms of Madelung lipomatosis:.

multiple symmetrical painful lipomatous nodes in the lymph nodes of the neck;

malformations of the skeleton, dysplasia of the distal growth zone of the radius;

breathing disorders;

dysphagia;

muscle weakness;

tachycardia;

angina;

dysarthria;

headaches.

Multiple Roche-Leri lipomatosis is characterized by the predominant localization of lipomas in the lower third of the body, on the upper extremities, in the groin, gluteal regions. In this case, parts of the body above the level of the nipples and below the knee joints are not affected.. Fatty growths are symmetrical elastic subcutaneous formations, usually painless. The appearance of this pathology is associated with a hereditary predisposition, the disease manifests itself after 25-30 years.

Given that in most cases lipomas develop against the background of impaired fat metabolism, its normalization seems to be the main measure for the prevention of lipomatosis..

If lipomatosis of the skin leads mainly only to an aesthetic defect, then the growth of adipose tissue in the internal organs poses a serious threat to health..

Liver lipomatosis - fatty liver. The exact mechanism of the formation of the pathology has not been elucidated, however, it has been established that the deposition of adipose tissue in the liver occurs due to an abnormal increase in the level of lipids in the blood with obesity, alcohol abuse, liver diseases. Clinically manifested by painful sensations in the right side, general malaise, decreased appetite, enlarged liver.

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