Scientists at the University of Wisconsin at Madison found that anti-opioid antibodies were produced in most patients with back pain who took opioid pain relievers they examined..

They can contribute to some of the negative side effects associated with long-term use of this class of drugs.. They may also limit the benefits a patient receives from an opioid vaccine, the production of which is the ultimate goal of this line of work.. A vaccine that stimulates the immune response against opioids may reduce the harm from opioid abuse, but researchers need to identify a group of patients who will respond well to this treatment..

Cody Ventour, professor at the University of Wisconsin School of Pharmacy, supervised and presented findings.

Scientists find protein-bound antibodies against opioids in 10 out of 19 patients taking opioids for chronic low back pain. Those who took higher doses had a stronger antibody response. A control group of three patients who did not take opioids for back pain had very low levels of anti-opioid antibodies.

https: // www. medikforum. ru /.

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