Cancer Gene Therapy

05 February 2020, 04:05 | Health
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Tumors can interfere with the functioning of the immune system, creating an environment unfavorable for immune cells, but scientists are trying to overcome the protection of cancer with interferons and cytokines..

Unfortunately, the systemic use of these substances is limited due to their high toxicity..

When delivered directly to the tumor, interferons can weaken the cancer’s protective barriers and allow the immune system to do its job..

This is exactly the strategy suggested by Dr.

Luigi Naldini of the University of Vita Salute San Rafael (Milan).

Scientists report in Science Translational Medicine that they modified monocytes that secrete interferon alpha, causing them to penetrate the tumor faster and “poison” it from the inside.

In an animal model of breast (mouse) cancer, a new approach has helped permanently stop tumor growth without visible side effects..

Scientists said their method "

medbe. ru.

Based on materials: medbe.ru



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