In recent years, there has been a steady increase in the number of people suffering from genital warts.. Despite the fact that this pathology occurs in only 1% of the sexually active population, according to the online publication for girls and women from 14 to 35 years old Pannochka. net Condylomas are one of the types of viral warts that occur more often in the anogenital area, and mechanical damage can result in bleeding and infection.. Also, this disease can trigger the development of cervical and penile cancer..
This pathology causes dyspareunia, which leads to sexual dissatisfaction, decreased sex drive, lack of sexual contact, depression. Despite the fact that in the initial stages of the disease of the patient, only subjective discomfort worries, do not forget about the epidemiological danger, as well as the possibility of the virus causing cancer.
The causative agent is the human papillomavirus, which is mainly transmitted through vaginal, oral, anal sexual contact with an infected person. In 90% of cases, genital papillomavirus of types 6 and 11 is responsible for the occurrence of genital warts of the anogenital region.
There are several possible types of treatment and their combinations, depending on the specific situation.. To eliminate skin manifestations, destructive methods are used: chemical, physical, surgical. For pathogenetic therapy, and in order to lengthen the relapse-free period, antiproliferative, antiviral and immunological methods are used.. The latter, at the moment, have firmly taken a niche in complex therapy, and are used in conjunction with destructive methods of treatment. This combination allows you to quickly relieve the patient of clinical manifestations, and the use of immunotherapy can reduce the frequency of relapse of the disease.
A third of patients are independently cured of genital warts, due to the activation of antiviral immunity. The action of drugs of this group is aimed at certain parts of the immune system. Such therapy is used for difficult to treat condylomas, massive skin lesions and a relapsing course of the disease..
The most studied immunomodulating agent is imichimod (imiquimod). It activates apoptosis, stimulates the synthesis of interferon-alpha, tumor necrosis factor alpha and interleukin-6, also normalizes cellular immunity.
In 2001, a review of the results of six major studies was conducted, which allowed us to argue that the use of imichimod (imiquimod) in the treatment of genital warts is more effective than placebo.
A large number of treatment options for genital warts, mainly mechanical removal, do not affect the cause of their appearance - human papillomavirus. The presence of drugs that activate the production of pro-inflammatory cytokines and inhibit the replication of the virus allows you to think about a possible cure for the patient from this pathology..
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