Quincke's edema (angioedema) is a type of allergic reaction that is characterized by the occurrence of edema of the skin, mucous membranes, subcutaneous fat.

This pathology accounts for approximately 2% of all cases of allergies.. Angioneurotic edema occurs in all age groups of patients, however, children and young women are more prone to its development.. In children of the first months of life, the disease is particularly difficult, often ending in death. The hereditary form of pathology is most often found in male patients.

Quincke edema often develops in the area of \u200b\u200bthe lips; the prognosis depends on the severity of the course of the disease and the timeliness of therapy. With the hereditary form, relapses are often observed throughout the patient's life.

Swelling in some cases may take place on its own and not require special treatment, however, a doctor’s consultation is still necessary.

Types of Angioedema may be:.

isolated;

combined with urticaria.

By the nature of the course - acute and chronic recurring.

In addition, it is congenital and acquired..

Causes of Quincke's Edema The main cause of the pathology is one or another form of allergy.

The cause of the development of the congenital form may be the insufficiency of the C1-inhibitor, which may consist in its insufficient production, and inadequate activity and increased use.

The acquired form of pathology can be observed if the patient has neoplasms of the lymphatic system, a number of infectious and autoimmune diseases.

In about 1/4 of the total number of patients, the disease is due to a genetic predisposition, in 30% of cases it is acquired, in the remaining patients it is not possible to find the exact cause.

If it is not possible to determine the etiology of the pathological condition, the patient is diagnosed with idiopathic angioedema.

The table shows a number of allergens, under the influence of which the development of the pathological process can occur.

Allergens group.

Explanation.

Food.

Most often, fruits, nuts, eggs, milk, honey, fish, chocolate, nutritional supplements.

Medicines.

Often antibiotics, B vitamins, anesthetics, antihypertensive drugs (angiotensin II receptor antagonists, angiotensin converting enzyme inhibitors), oral contraceptives.

Plant pollen.

Birch, hazel, alder, fescue, wormwood, quinoa, any flowering plants.

Chemicals.

Especially household chemicals, cosmetic preparations, turpentine, phenol.

Dust.

Mostly home and library.

Microorganisms.

Viruses, bacteria, microscopic fungi.

Pets, insects.

Animal hair, bird feathers, food for aquarium fish, insect venom.

Also, the pathological process can develop with a false allergy (pseudo-allergy), in which a person has an increased sensitivity to certain drugs, food products in the absence of an immunological stage.

Risk factors include helminthic infestations, endocrine diseases, some diseases of the internal organs. In young children, a predisposition to allergic reactions can provoke the use of cow's milk.

Stressful situations, the use of alcoholic beverages, damage to the mucous membranes, and hypothermia can also contribute..

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