Nowadays, hyaluronic acid is widely used both to eliminate cosmetic defects and to treat joint pain caused by osteoarthritis.. Injections of hyaluronic acid can be both a means of rejuvenation and treatment.

Hyaluronic injections for rejuvenation In recent years, the list of drugs used to rejuvenate the skin has been significantly expanded without surgery.. Various anti-aging injections have become popular since the first injections of botulinum toxin, better known as Botox Botox: in search of eternal youth. Today, Botox in most countries remains the most popular means for non-surgical rejuvenation, and hyaluronic acid holds the fifth place in the popularity rating. Hyaluronic acid is the keeper of youthful skin after laser face resurfacing.. By the way, hyaluronic acid in ampoules is used externally - it rejuvenates the skin quite well, but injections, of course, are much more effective..

Currently, as excipients, the following types of drugs with hyaluronic acid: Hylaform, Hylaform Plus, Captique, Restylane, Juvederm Ultra, Juvederm Ultra Plus. A few more drugs, including new types of Restilan, are now undergoing clinical trials..

Hyaluronic acid is a natural substance, biopolymer, which is an essential component of the intercellular matrix of the tissues of all animals..

The first hyaluronic acid filler was developed in 1989; it was not as effective as modern fillers, but research began with it, which led to the fact that today many people can look much younger thanks to hyaluronic acid.

The most important characteristics of preparations based on hyaluronic acid are: the source of the acid, its concentration, the particle size, and also whether the hyaluronic acid is monophasic or biphasic.. Now hyaluronic acid, used for rejuvenation, is obtained either from chicken scallops or synthesized with the help of bacteria Staphylococcus equine. The latter source is now becoming increasingly popular, because when using hyaluronic acid derived from chicken scallops, there is a possibility of allergic reactions in some patients.

The concentration of hyaluronic acid in the preparations determines how durable the effect of the injection will be..

The most effective are drugs with a concentration of hyaluronic acid of 20 mg / g or more..

The effect depends on the particle size of hyaluronic acid: drugs with larger particles are used to smooth the most deep wrinkles, and to obtain the most stable result.

Hylaform was the first hyaluronic acid filler, the use of which was officially approved for skin rejuvenation. It is used to smooth out medium to moderate wrinkles and folds.. Hylaform is not recommended for lip augmentation.. Its main disadvantage is that the results of injections of this drug are stored only for three to four months.. Hylaform Plus has a slightly larger particle size than Hylaform, but the effect of its use is also rarely lasting for more than four months.. However, these drugs cause only very minor side effects, so they are often recommended for those who need to make rejuvenation as quickly as possible, avoiding a long recovery period..

Captique is used to eliminate shallow folds and wrinkles.. The effect lasts for three to six months..

Restylane is currently one of the most well-known hyaluronic acid fillers.. It is used to smooth deep wrinkles, enlarge lips and correct nasolabial folds..

Restilan's clinical trials began in the 1990s. A report from one of the studies states that in 78% of patients, a significant improvement in the skin after injection was observed within eight months after the procedure.. At the same time, in 13% of subjects, such effects of hyaluronic acid injections were noted, such as hyperpigmentation of the skin in the injection area, erythema (reddening of the skin as a result of the expansion of small blood vessels), as well as mild and moderate pain. However, according to studies conducted already in the 21st century, only 0 were observed with undesirable effects of hyaluronic acid injections.. 02% of patients.

Juvederm is also used to combat deep folds and wrinkles..

Due to the high concentration of hyaluronic acid, this drug is probably the most effective of all hyaluronic acid fillers, but no studies have yet been conducted that could confirm these assumptions.. Results of Juvederm injections persist for 6-12 months.. This filler rarely causes any side effects, besides, some experts believe that the result of its use looks more natural than the results that can be achieved with the help of other fillers..

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