Employees of the Medical School Wake Forest want to make a medicine that, first of all, will not be addictive.

The experimental drug AT-121 has already been tested on animals. It not only effectively eliminates pain, but also allows you to abandon the use of opioid pain relievers. This is reported by MedDaily referring to the medicalxpress. com.

AT-121 affects both the opioid receptor mu (this is how the most powerful pain relievers work), and the nociceptin receptor (blocks the dependence and the negative effects caused by the effect on the mu receptor). Opioid drugs like oxycodone and fentanyl only work with the mu receptor and provoke side effects? respiratory depression, dependence, hypersensitivity to pain.

As the experiment showed, AT-121 gave the same relief as opioid drugs, but the dose was 100 times lower than the dose of morphine used. In parallel, the new agent relaxed the dependence on oxycodone.

yellmed. en.

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