Scientists from the Swiss Higher Technical School of Zurich are working on a therapy that will replace Viagra. In the penis of men suffering from erectile dysfunction, the genetic construct created by specialists will be introduced. Under the influence of blue light, blood flow to the site of insertion of the construct will increase, leading to an erection without additional stimulation.
Experts have developed a genetic construct for 4 years. They conducted an experiment on male rats, which was successful. Researchers have introduced a construct in the erectile tissue of experimental animals. In most cases, blue light "included" an erection in rodents. Some animals even had ejaculation.
Scientists explain: as soon as the erectile tissue with the construct is exposed to blue light, the precursor molecule guanosine triphosphate (GTP) is converted into a secondary carrier cyclic guanosine monophosphate (cGMP). Calcium channels close, and the level of calcium in the cells decreases. Because of this, muscle cells relax, and the flow of blood to the erectile tissue increases. There is an erection, which eventually passes, as cGMP is destroyed.
Viagra, which is currently used to treat erectile dysfunction, blocks the action of the enzyme that destroys cGMP, so that the erection lasts longer. However, to call it this tablet is not capable. According to scientists, the likelihood of side effects from their therapy is small. The injection itself is relatively painless, and before the other organs the introduced genetic construct is unlikely to get. Tests in humans have not yet been carried out, but scientists are convinced: gene therapy will help men suffering from erectile dysfunction.
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