Doctors told why sitting on a chair is dangerous to health

03 June 2018, 12:03 | Health
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Scientists have established: if a person does not load the muscles of his legs, his brain begins to quickly fade away. A group of Italian researchers from the universities of Milan and Pavia shared the results of their work, during which it was found that the lack of proper loads on the legs adversely affects the brain. Scientists say that during physical exertion on the muscles of the legs, the brain receives signals that are vital for the normal functioning of the nervous system as a whole.

"The absence of such loads leads to a sharp reduction in the production of new neurons in nerve cells, on which the ability to cope with stress and adapt to changing environmental conditions depends," the authors of the study stated in the pages of Frontiers in Neuroscience.

Scientists conducted an experiment on laboratory mice that were not allowed to use their hind legs for 28 days. At the same time, good nutrition and comfortable conditions were organized, and the animals showed no signs of stress. The lack of physical activity for the hind legs in mice resulted in a 70% reduction in the number of neural stem cells in the subventricular zone, the area of ??the brain responsible for maintaining the normal functioning of the nervous system. In addition, in the brain of such mice, neurons and the cells protecting the nervous system, oligodendrocytes. Note that the science knows this fact: in patients with diseases that deprive them of the ability to walk and load the muscles of their legs, cognitive abilities. Working leg muscles provide brain health, scientists are no doubt now.



"With a sedentary lifestyle, pathological changes occur at the cellular and genetic level that alter the metabolism and affect the function of mitochondria in cells. - energy "substations" cells. The results obtained can explain the negative consequences of a sedentary lifestyle and can help understand the biological processes occurring in such severe neurological diseases as multiple sclerosis, spinal muscular atrophy, amyotrophic lateral sclerosis, "the authors of the project.

Source: News Yu.

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