The world's largest study examining the relationship between vitamin D levels and hypertension, found that this vitamin does affect the regulation of blood pressure.

Scientists presented their results at the annual conference of the European Society of Human Genetics (ESHG).

The data were obtained from an analysis of 35 studies that involved more than 155,000 people from different parts of Europe and North America. This grandiose work was headed by Dr. Vimal Karani, a member of the Institute of Child Health of University College London.

Participants with a high serum level of 25-hydroxycalciferol (25-hydroxyvitamin D, or 25 (OH) D) had lower blood pressure and a relatively lower risk of developing hypertension.

Dr. Vimal Karani says: "We knew from early observations that low concentrations of 25 (OH) D are more often associated with increased blood pressure and the development of hypertension, but this relationship has been poorly understood. In addition, randomized controlled trials of vitamin D in humans have shown mixed results for cardiovascular outcomes. The overall picture is fuzzy, so we decided to conduct our analysis and clarify this issue ".

In the course of the work, to study the relationship between vitamin D levels and arterial pressure, scientists used point genetic variations called SNPs as markers. They found that with an increase in the concentration of 25 (OH) D for every 10%, the risk of developing hypertension is reduced by an average of 8.1%. Dr. Karani said that their approach to analysis, called Mendel's randomization, made it possible to draw accurate conclusions.

Researchers say that vitamin D deficiency is a very common problem in the Western world, in part because obesity can cause a shortage of this vitamin in the body. As you know, a person has two ways to get vitamin D - eating with food or drugs and synthesis in the skin under the influence of ultraviolet rays.

People with a high level of vitamin D can immediately count on several significant health benefits, and this, in addition to increasing the strength of bone tissue. Researchers at the School of Medicine at Boston University in PLOS ONE reported that vitamin D increases immunity, as well as reducing the risk of cancer, infections, type 2 diabetes, certain autoimmune diseases and CVD.

Dr. Karani's research added new data on the role of this vitamin in maintaining our health.

Scientists have concluded that a high concentration of 25 (OH) D in the blood reduces the risk of hypertension, and with it the risk of fatal cardiovascular events.

The doctor concluded: "Now we intend to continue work on the study of the causal relationship between the level of vitamin D in the body and other cardiovascular risk factors, such as dyslipidemia, C-reactive protein, the level of type 2 diabetes markers, etc.. We are sure that science still has a lot to learn about the influence of vitamin D on human health ".

medbe. en.