A small molecule with a large name can block the ubiquitous polyomaviruses that cause serious illness in people with a suppressed immune system, according to an Internet publication for girls and women aged 14 to 35 Pannochka. In culture, the 2 - {[(5-methyl-2-thienyl) methylene] amino} -N-phenylbenzamide molecule effectively blocked cell infection by several types of polyomaviruses.

These results were reported by Dr. Walter Atwood of Brown University in Providence.

Poliomavirus chronic infection is detected in 50-80% of the population, but usually it does not cause any symptoms.

In people with reduced immunity, polyomaviruses can lead to progressive multifocal leukoencephalopathy.

In the publication of mBio, scientists reported that a new molecule, which for short is called Retro-2cycl, blocks the transport of polyomaviruses to the endoplasmic reticulum, that is, the critical stage of the reproduction of the virus is disrupted.

To date, according to scientists, there are no ways to treat poliomavirus infection.

But they proved that the new substance Retro-2cycl limits the spread of the virus with a confirmed infection, which means that it can be used as a basis for future therapy.

medbe. en.

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