Scientists from the University of Georgia (USA) found that the hormones responsible for human aging and chronic diseases are determined by our heredity, according to the Internet publication for girls and women from 14 to 35 years old Pannochka. net Now it became clear why in some families there are many long-livers, and in others many hardly have time to exchange their fifty kopecks.

The last study was devoted to a hormone called Growth Differentiation Factor 11 (GDF11), whose content in the blood decreases as it ages.

In 2014, an unusual experiment was conducted, when scientists increased the GDF11 content in the body of mice, thereby rejuvenating their cardiovascular system, muscles and brain. This discovery was called one of the greatest discoveries of the year.

Now, the staff of the UGA Family College found that the level of GDF11 is determined by our genetics. This has become another mechanism, explaining how nature even before birth measures our age. Destiny, if you want.

In the future, scientists are going to explain how and why the content of GDF11 decreases with age. Why does the average age of GDF11 level drop dramatically, turning the last page of our active and carefree life. And, most importantly, how to stop this process and keep youth as long as possible.

"The fact that the aging hormone is under the control of genes is a discovery of great interest. If there are genes that are responsible for the level of GDF11, then there are ways to change them, "says the lead author of the study, Dr. Rob Pazdro, a researcher at the UGA Dietetics Department.

The experiences of Dr. Pasdro and his colleagues demonstrated a clear link between the level of GDF11, aging markers and life span in 22 genetically heterogeneous mouse strains. At the same rodents with the highest concentration of hormones lived much longer and were better preserved in old age.

With the help of genetic mapping, the Pazdro team identified 7 candidate genes that are most suitable for the role of GDF11 regulators. They were the first to prove that the level of GDF11 strongly depends on heredity.

"We found the missing piece of the puzzle called" Genetics of Aging ". This is a significant step towards understanding the genetic basis of aging. We have approached the lever that controls this complex, irreversible and tragic phenomenon. This is the first step of science on the long journey, but it is very, very important, "concluded Dr. Pasdro.

The results of the study were published in Journals of Gerontology Series A Biological Sciences and Medical Sciences.

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