Ginger can be an effective medicine against inflammatory bowel diseases (IBD) if taken in the form of special nanoparticles, according to the Internet edition for girls and women from 14 to 35 years old Pannochka. net The original method of treating a serious illness is reported in the journal Biomaterials.
Recall that the group of inflammatory bowel diseases include Crohn's disease and ulcerative colitis (NJC) - severe chronic diseases, which are based on mysterious autoimmune mechanisms.
People with Crohn's disease and NJA complain of persistent abdominal pain and diarrhea; sometimes bleeding occurs, anemia, weakness, hypovitaminosis.
In search of effective drug delivery methods, the University of Georgia (USA) created nanoparticles from the rhizome of the ginger, which allow the treatment of IBD with minimal doses without undesirable side effects.
For thousands of years, ginger has been used in traditional medicine of many peoples. Since ancient times, it has been a remedy for colds, nausea, arthritis, migraine, hypertension. It was used in dried form, powders, candies, extracts.
Equally popular is ginger in cooking. It is believed that ginger tea normalizes digestion.
Researchers from the Atlanta Veterans Association and the Institute of Biomedical Sciences at the University of Georgia for the first time used a unique form of ginger - nanoparticles GDNP (ginger-derived nanoparticles) obtained by high-speed centrifugation.
Dr. Didier Merlin began to work with ginger for a long time, getting juice from his rhizomes on an ordinary kitchen blender.
Later, after studying the composition of medicinal juice, the scientist separated nanoparticles with a diameter of about 230 nanometers with the help of a centrifuge - this is less than the thickness of a human hair. Such particles are able to easily penetrate into tissues and fight inflammatory processes.
In experiments on mice, ginger nanoparticles significantly reduced the risk of developing acute and chronic colitis, as well as such a formidable complication as colitis-associated bowel cancer. The secret of their action is that the particles increase the vitality of the cells of the intestinal mucosa and inhibit the production of inflammatory mediators.
According to the authors, the nanoparticles contain a large amount of lipids, including phosphatidic acid (membrane protection), as well as substances called 6-gingerol (antioxidant) and 6-shogaool (a promising cancer molecule). This complex of substances causes anti-inflammatory, antioxidant, antitumor and anti-emetic properties of ginger.
When introduced into the gastrointestinal tract, the ginger nanoparticles are well distributed among the cells of the intestinal mucosa and penetrate them. The drug was well tolerated by animals; no serious adverse event was reported.
Cheapness, availability and high therapeutic efficiency - it is these properties that will have a new nanopreparation based on ginger. Scientists hope that its finalization and clinical trials will be completed in the next 3-5 years.
medbe. en.
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