Researchers at Cambridge University found that an overactive immune system causes inflammation throughout the body, leading to depression, feelings of hopelessness and fatigue. Experts are convinced that depression is a physical disease caused by a defective immune system, and this disease can be treated with anti-inflammatory drugs. Modern methods of treating depression are focused on the restoration of serotonin and other chemical compounds in the brain.
Preliminary clinical trials have shown that treating inflammation can alleviate the symptoms of depression. Next year, experts hope to begin trials to test whether anti-inflammatory drugs can suppress depression.
"It's clear that inflammation can cause depression," says Professor Ed Bullmore. The immune system causes an inflammatory response when it senses that the body is at risk - this leads to large-scale changes in the body, such as an increase in the number of red blood cells.
As a result, the immune system can not disconnect after an injury or illness, while maintaining increased activity, so that people can suffer from a depressed mood.
When doctors give people drugs to strengthen the immune system to fight the disease, treatment is often accompanied by depressive symptoms - just like many people feel depressed after vaccination. According to doctors, the results can lead to the emergence of such a new field in medicine as immunoneurology.
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