In the treatment of mastitis, paramount importance undoubtedly belongs to surgical intervention and antibiotic therapy. However, antibiotics do not always allow to achieve the expected result, especially in the treatment of infection caused by a resistant microflora, or because of intolerance to antibiotics by patients, so an important task is to maintain the immunological homeostasis of patients with drugs that affect various parts of immunity: phagocytosis, complement system , macrophages, T- and B-lymphocytes, cytokines, the level of immunoglobulins.

The use of any of them should be pathogenetically justified, t. determined by the nature of the detected disorders of the immune system. Not all patients, the administration of drugs, even multiple, leads to a stimulating effect. This is explained by the influence of genetic mechanisms, the age of patients, the dose of the drug, the scheme of its administration, the prevalence of the purulent process, and t.

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