Chemoprophylaxis of cancer - the use of pharmacological or natural agents to prevent the occurrence of malignant tumors, as reported by the Internet publication for girls and women from 14 to 35 years Pannochka. net Clinical studies have revealed drugs that reduce the incidence of breast, prostate, liver, skin, stomach and other localizations in patients with high oncological risk groups. A number of agents have been found capable of causing regression of precancerous conditions and changes in various organs. The widespread use of chemopreventive drugs should be an effective measure to reduce cancer morbidity and mortality.

Epidemiology of malignant tumors.

In Russia and in many other countries of the world there is an increase in oncological morbidity. In the year 2005. in our country there were 469195 new cases of cancer, a rough incidence rate per 100,000 population was 330.5, an increase over the 10-year period was 17.4%. Despite the progress in the treatment of cancer, in general, mortality from malignant tumors in Russia does not decrease. In the year 2005. from cancer, 285,402 people died; a rough death rate was 200.6 per 100,000 population, for a 10-year period this figure did not change significantly. At the same time in a number of economically developed countries in recent years, morbidity and mortality from many forms of cancer have been reduced, which was achieved due to the active use of scientifically based measures for the prevention of malignant tumors.

Prophylaxis and chemoprophylaxis of cancer.

The most promising ways of preventing malignant tumors today are the fight against smoking; normalization of nutrition; screening for the timely detection and treatment of precancerous conditions and changes and early forms of cancer; chemoprevention. Specific weight of nutritional factors among the causes of malignant tumors is 35%, whereas the next most important factor - smoking - causes 30% of cancers. In this regard, dietary cancer prevention can be considered as the most effective way of anti-cancer fighting. The use of food anti-carcinogenic substances is also one of the directions of chemoprevention of cancer.

According to the definition of the International Agency for the Study of Cancer, chemoprophylaxis of oncological diseases is the use of pharmacological or natural agents to prevent the occurrence of cancer. Means for chemoprophylaxis of cancer should meet the following requirements: 1) proven effectiveness - the ability to prevent the occurrence of malignant tumors; 2) the possibility of applying for a long time; 3) absence of toxic effects or minimal toxicity; 4) desirable additional favorable properties; 5) dosage forms - oral or topical only.

health. sumy. ua.

Keywords:.