Regeneration of tissues as in salamanders and newts seems to be the subject of science fiction. But this happens in reality. Why do we, mammals, not be able to restore a limb or grow a new heart muscle, when necessary?.

The new study suggests that for this there must be a valid reason: limiting our cells' ability to enter the cell cycle at their own discretion is a necessary condition for dividing cells for the construction of a new tissue - reduces the likelihood that they will get out of control and lead to the formation of deadly Cancerous tumors, according to the Internet edition for girls and women from 14 to 35 years old Pannochka. Net Scientists at the Stanford University School of Medicine have taken a big step toward the possibility of regaining the ability to regenerate muscle cells of mammals. They achieved such results in experiments on laboratory mice, blocking the expression of only two genes that suppress the development of tumors. Opening can bring medicine closer to restorative therapy in humans - surprisingly, but directing us down the evolutionary ladder.

"Tritons are very effective in restoring their tissues," says Dr. Helen Blau, a researcher at the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University,. "Mammals just cause pity. We can restore our liver, and that's all.. Until today, the way they do it has remained a mystery ".

Helen Blau is the lead author of the study, whose results are published in the journal Cell Stem Cell.

Against the backdrop of a large number of discussions about the use of adults or embryonic stem cells to restore and rejuvenate the tissues of the entire body, researchers have chosen a different pathway. Instead of stem cells, they studied the question of whether it is possible to force the myocytes, usually non-muscle cells, to re-enter the cell cycle and begin to proliferate. This is a very important question, because the specialized, or differentiated, mammalian cells are fixed in a stable condition, prohibiting cell division. To achieve the same regeneration without cell division is not possible.

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