American biologists in experiments on mice found out why fasting prolongs life, while physical stress on its duration does not affect - as it turned out, a meager diet forms a favorable hormonal background, conducive to longevity, according to the Internet edition for girls and women from 14 to 35 years old Pannochka. Net In an article published in the American Journal of Physiology, researchers note that the effect of increasing life expectancy in mice with limited nutrition is known for a long time, as well as the fact that physical stress does not lead to the same effect.

"We know that the skinners are better than the thick are protected from many diseases. However, studies of rodents have shown that they live longer if they have a reduced weight because of a meager diet. Physical stress, also causing weight loss, does not give such an advantage. Our research was undertaken to find out why this is the case, "said study lead author Derek Huffman of the Albert Einstein Medical College in New York. Huffman's words are given in the message of the American Society of Physiologists (American Physiological Society), which is engaged in the publication of the journal. The scientist emphasizes that these data refer specifically to rodents, which in many ways differ from people. At the same time, he adds, recent studies have led to similar results for people. As it turned out, people who follow a strict diet are more likely to live longer than those who do not limit themselves to eating, but get serious physical activity. One of the hypotheses explained this effect in that physical stress causes stress, which damages tissues and DNA. According to another point of view, the use of the caloric restriction of food. Investigating two groups of mice, one of which was restricted in food and the other subjected to physical stress, the researchers found that both groups had a level of marker (8-hydroxyguanosine) indicating a DNA damage. In this case, the animals that received as much food as they wanted, and were not subjected to physical exertion, the level of this marker was very high. Thus, the first hypothesis was refuted - the researchers came to the conclusion that the degree of damage to DNA and tissues increases with age, is accelerated by obesity, but slowed down by a low-calorie diet and / or physical exertion. "Instead, the study showed that restrictions on the caloric content of food lead to favorable changes in the hormonal background of the body, which does not cause physical stress. Scientists came to the conclusion that these changes in metabolism contribute to the prolongation of life, "the message says..

Huffman emphasizes that the benefits of physical exercise for people are higher than in mice, since people are more predisposed to cardiovascular disease, which can be prevented by regular training. "I do not want to say that the results of this research can be applied to people already now. But it shows what physiological changes cause physical exercise and caloric restriction of food. We can continue these studies until we understand how this works with people, "he said..

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