A new study published in the journal PLoS Biology sheds light on how damaged skin cells and nerve sensory fibers coordinate their regeneration in the healing process of the wound, writes The Times of India.
Sandra Rieger and Alvaro Sagasti, researchers at the University of California, found that hydrogen peroxide, a chemical signal emitted by damaged skin cells, helps regenerate sensory fibers, making sure that the ability to feel the touch has returned to the skin, according to an online edition for girls and women from 14 to 35 years old Pannochka. Net They found that reactive oxygen species that can be found in high concentrations in wounds are key components of this signal. In order to test whether the skin itself can contribute to the regeneration of axons (nerve cell processes), scientists amputated the tip of the tail in the larva of Danio rerio and began observing the behavior of nearby peripheral sensory axons.
It turned out that amputation activated the growth of axons and allowed the axons to penetrate into regions of the skin, which under normal circumstances would have been rejected.
It has also been shown that damage to skin cells in any part of the body resulted in the regeneration of nearby sensory axons. It turned out, damaged skin cells were the source of the signal.
The addition of hydrogen peroxide to the substrate of the damaged larva led to a repetition of the effect provoking the growth of axons. But the blocking of hydrogen peroxide production threatened to stop the mechanism, which allows to start the regeneration of axons.
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