Scientists have identified more than 20 combinations in the human genetic code that contribute to the emergence of hypertensive disease. The authors of the study, published in the scientific journal Nature, hope that these data will help in the development of new methods of treating hypertension, according to the Internet publication for girls and women from 14 to 35 years old Pannochka. Net British cardiology fund in this regard said that in his opinion, the leading factor in the onset of hypertension is the way of life.
Scientists have long known that hypertension is hereditary, meeting with representatives of one family is especially frequent. At the same time, factors such as obesity, lack of physical activity and excess salt can complicate the course of the disease. The impact of these factors is fairly well understood, but the genetic nature of hypertension is not fully understood by scientists.
And now the researchers say that they have achieved great success in understanding the role of genes for the emergence and development of hypertension in humans. In the first of two studies, scientists from 24 countries analyzed data on more than 200 thousand patients with hypertension. They established 16 new gene combinations that are associated with increased blood pressure.
Professor Mark Caulfield of the Barts Hospital and the London School of Medicine stated that one or other variants of such gene combinations are present in 14% of people. Detection of the genetic basis of hypertension also sheds light on certain processes in the body that may be exposed to new drugs in the future.
For example, studies in the field of chemical reactions involving nitric oxide, which facilitates the relaxation of smooth muscle vessels and their expansion, give hope for the development of completely new methods of treating hypertension. "There is a significant potential for the transfer of these scientific results from the laboratory to the clinic," said Professor Caulfield.
However, researchers believe that to date, only 1% of combinations of the genetic code that are associated with increased blood pressure.
News. Gradusnik. En.