Usually, the increased fat content of the skin is associated with acne. However, oily skin in itself is a cosmetic defect, which many people face and fight with it for many years. Now science has made a big step forward in researching the reasons why the skin secrets more than necessary, sebum, why it is needed, what its functions are and whether it is possible to influence the functioning of the sebaceous glands, according to the Internet edition for girls and women From 14 to 35 years old Pannochka. Net It should be noted that one of the main stimuli for increasing the production of sebum is the special substances androgens, t. Male sex hormones. Note that the sebaceous gland is directly affected not by testosterone itself, but DHT is the element into which testosterone is converted by the action of the enzyme 5-Alpha reductase.

Deep scientific research has shown that excessive fat content of the skin can manifest itself not only with the increase in blood or skin level of testosterone, but also with increased sensitivity of some sebaceous glands to the effects of DHT, with insufficient activity of aromatase enzymes that destroy DHT in the skin, and also with hyperactivity of 5 -Alfa-reductase in some sebaceous glands. Metabolism of estrogens (female sex hormones) also affects the sebaceous glands, as they are natural testosterone antagonists. Recently, data have been obtained that suggest that the skin is capable of synthesizing steroid hormones from DHEA or even cholesterol. In this case, the sebocytes are responsible for the synthesis, and the keratinocytes are responsible for the destruction of androgens.

When it became clear that the androgens are not, as previously thought, the only stimulus for the sebaceous glands, the situation is even more complicated. It turns out that some substances that are excreted by the nerve endings of the skin (one of them is called substance P), can also stimulate the increase in sebaceous glands and the production of sebum. So, substances that irritate the skin (and many drugs used in the treatment of acne, skin irritate), can provoke the appearance in the skin of substances that the sebaceous glands command to grow and increase productivity.

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