Scott McTominay and Bruna Fernandes scored two goals each, while Leeds striker Rafinha gave two assists (6: 2).
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Manchester United 6-2 Leeds United Goals: McTominay, 2, 3, Fernandes, 20, 70 (pens. ), Lindelof, 37, James, 66 - Cooper, 42, Dallas, 74 Manchester United: De Gea - Van Bissaka, Lindelof, Maguire, Shaw (Alex Telles, 61) - McTominay, Fred James, Fernandes (van de Beek.
Leeds United: Meslie - Dallas, Ayling, Cooper (Davis, 72), Alioski - Phillips (Strike, 46) - Rafinha, Rodrigo, Klich (Shackleton, 46), Harrison - Bamford.
Warnings: James.