Loss of muscle mass leads to aging

14 October 2018, 11:54 | Sports
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With age, muscle mass is lost, and the muscles weaken. Scientists from Columbia University believe that this is one of the main causes of aging and deteriorating health. In their opinion, tissue is important for metabolic processes.. Perhaps by developing a method to stop this process, it will be possible to prolong a person’s life, American researchers believe, according to the online publication for girls and women from 14 to 35 years old Pannochka. net As for the mechanisms of destruction of muscle tissue, little is still known about them.. According to one theory, free radicals give damage.. Scientists have bred mice in which less free radicals were released in the mitochondria. This has increased the life expectancy by about 20%..

Specialists have found that calcium is an important factor in the health of muscle tissue.. His release caused the muscles to contract.. Responsible for the release of the molecule - ryanodinovy ??receptor 1. It was he who became the target of free radicals.. And as it gets older, calcium started to leak when it shouldn't. It weakened the muscle fibers..



Tests have shown that in genetically modified rodents the receptor suffered less from radicals.. Moreover, their muscles were stronger. At this stage, scientists are testing drugs that prevent calcium leakage.. There is another option - a compound that shifts the balance towards greater growth of muscle tissue, rather than its decomposition.. In particular, it is under the power of bimagrumab - a compound that blocks the signaling pathway associated with the muscle growth inhibitor myostatin.

medicinform. net.

Based on materials: pannochka.net



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