Swedish researchers from the Karolinska Institute have shown that long-term endurance training changes the activity of genes, having a positive effect on carbohydrate metabolism and inflammation..

The study involved 23 healthy young volunteers of both sexes.. The subjects were asked for three months four times a week for 45 minutes to turn the pedal of the exercise bike. It was one pedal, one leg that had to remain untrained and act as a control.. From both legs of each volunteer took a small piece of muscle for biopsy. The researchers also measured the muscle strength of the volunteers' legs before and after the training course..

Analysis of the work of 20 thousand.

of genes in muscle fibers revealed that compared to untrained muscles, genes regulating carbohydrate metabolism and adaptation to physical activity are more actively expressed in trained ones. In addition, genes that enhance inflammation in the trained muscles were less active..

Experts believe that the results of the study will help to find new effective approaches in the treatment of diseases such as diabetes and cardiovascular diseases - conditions associated with inflammation and carbohydrate metabolism..

medicinform. net.