General information about Brilinta What Brilinta is used for?
Brilint 90 mg tablets are used to prevent blood clots (thrombosis) in people with cardiovascular disease, especially acute coronary disease such as a recent heart attack (myocardial infarction) or unstable angina (chest pain), to reduce the risk of another heart attack. or stroke, and to reduce the risk of death from cardiovascular disease. Brilinta 90 mg tablets should be used in addition to aspirin, which is another anti-clotting drug that helps reduce the risk of another heart attack and prevent death due to cardiovascular disease.
How does Brilinta work
Brilinta 90mg tablets contain ticagrelor, a specific and potent inhibitor of platelet aggregation (clumping), which is part of the process that leads to the formation of a blood clot (thrombosis), blocking the damaged blood vessel and stopping bleeding.
Platelets (or platelets) can also aggregate when they come into contact with a ruptured atherosclerotic plaque, when the artery wall hardens due to cholesterol buildup, a process called atherosclerosis.
A blood clot formed in this way can eventually block an artery, cutting off the blood supply to various parts of the body.. This can lead to a heart attack if the coronary arteries (supplying blood to the heart) become blocked and the heart is starved of oxygen.; or a stroke, if the arteries leading to the brain become blocked, causing oxygen deprivation of the brain.
Platelet aggregation depends on a chemical called adenosine diphosphate (ADP), which activates platelet aggregation by binding to a platelet receptor called P2Y12. Ticagrelor in Brilint 90 mg tablets selectively and reversibly binds to the platelet P2Y12 receptor, blocking the action of adenosine and thereby inhibiting platelet activation and aggregation.. By inhibiting platelet aggregation at the site of damage to blood vessels due to atherosclerosis, Brilint 90 mg tablets support blood flow and reduce the risk of thrombosis in people with cardiovascular disease and risk of heart attack or stroke.
Ticagrelor in Brilinta 90mg tablets has a rapid onset of action and its effect lasts up to 8 hours. blocking the action of adenosine and thereby inhibiting platelet activation and aggregation. By inhibiting platelet aggregation at the site of damage to blood vessels due to atherosclerosis, Brilint 90 mg tablets support blood flow and reduce the risk of thrombosis in people with cardiovascular disease and risk of heart attack or stroke.
If you live in Kharkov, it will be very useful for you to know - Brilinta price Kharkiv Tikagrelor in Brilinta 90 mg tablets has a quick onset of action and its effect lasts up to 8 hours. blocking the action of adenosine and thereby inhibiting platelet activation and aggregation. By inhibiting platelet aggregation at the site of damage to blood vessels due to atherosclerosis, Brilint 90 mg tablets support blood flow and reduce the risk of thrombosis in people with cardiovascular disease and risk of heart attack or stroke. Ticagrelor in Brilinta 90mg tablets has a rapid onset of action and its effect lasts up to 8 hours.
What Brilinta contains?
Brilinta tablets contain the active ingredient ticagrelor 90 mg (you can buy ticagrelor 90 mg here), an inhibitor of platelet aggregation that is used in the treatment of acute cardiovascular disease to prevent thrombosis. They also contain mannitol (E421), dibasic calcium phosphate, magnesium stearate (E470b), sodium starch glycolate, hydroxypropyl cellulose (E463), talc, titanium dioxide (E171), iron oxide yellow (E172), polyethylene glycol 400, hypromellose (E464). angina pectoris (chest pain) to reduce the risk of another heart attack or stroke and reduce the risk of death from cardiovascular disease. Platelet aggregation leads to the formation of a blood clot (thrombosis), which clogs the damaged blood vessel and stops bleeding. In atherosclerotic arteries (the wall of the artery hardens due to cholesterol buildup), there is a risk that the atherosclerotic plaque may rupture and cause platelet aggregation and blood clots. which can block an artery, cutting off blood flow to the heart or brain, causing a heart attack or stroke. Ticagrelor in Brilinta 90 mg tablets binds to a specific platelet receptor, blocking adenosine-dependent platelet activation, which inhibits platelet aggregation. By inhibiting platelet aggregation at the site of blood vessel injury, Brilint 90 mg tablets support blood flow and reduce the risk of thrombosis in people with cardiovascular disease, which reduces the risk of heart attack or stroke.
What are the side effects of Brilinta?
The most commonly reported side effects when taking Brilint 90mg tablets include: bleeding and bruising more often than usual or increased bleeding time, epistaxis (epistaxis), gastrointestinal bleeding, shortness of breath (shortness of breath), abdominal pain, dyspepsia (indigestion). , constipation, dizziness, headache, rash, itching.
When not to use Brilinta?
You should not use Brilinta 90 mg tablets if you:.
you are allergic to ticagrelor or any of the ingredients of Brilinta are pregnant or breastfeeding have liver disease have a bleeding disorder such as a stomach ulcer or intracranial bleeding are undergoing surgery (including dental) you have bradycardia (low heart rate and do not have a pacemaker.
You can read the full instructions in Russian by clicking here - Brilinta instructions for use What drugs interact with Brilinta?
Some medicines interact with Brilinta 90 mg tablets and should not be taken while you are taking Brilinta or only after discussion and direction from your doctor:.
Drugs that cause a serious reaction to Brilinta: SSRI antidepressants such as paroxetine, sertraline, and citalopram, non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, blood thinners such as heparins and warfarin may increase the risk of bleeding.
Medications affecting Brilinta: the antifungal ketoconazole, the antibiotics clarithromycin and rifampicin, ritonavir and atazanavir for HIV, the anticonvulsants phenytoin, carbamazepine, and phenobarbital, the immunosuppressant cyclosporine, diltiazem for irregular heartbeat.
Drugs affected by Brilinta: statins such as simvastatin or atorvastatin for high cholesterol, cisapride for reflux, ergot alkaloids for migraine, digoxin for heart failure.
How to take Brilinta?
Brilinta 90 mg tablets should be taken whole with or without food. The starting dose should be a double loading dose: 2 Brilinta 90 mg tablets taken at the same time, then one tablet should be taken twice a day in the morning and evening and at the same time each day in combination with aspirin as recommended by a physician. You must continue taking Brilint 90 mg tablets for 12 months and you must not stop taking Brilint 90 mg tablets unless your doctor tells you otherwise, as this may increase your risk of heart attack or stroke.
How long should I take Brilinta?
You must continue taking Brilint 90 mg tablets for 12 months and you must not stop taking Brilint 90 mg tablets unless your doctor tells you otherwise, as this may increase your risk of heart attack or stroke.
Missed dose of Brilinta If you miss a dose of Brilinta 90mg tablets, take it as soon as you remember, if it is not time for your next dose, then skip the missed dose. Don't double dose.
How should Brilinta be stored
Brilinta 90 mg tablets should be stored below 25°C in a cool dry place.