Weight loss and obesity centers. In modern literature, you can find indications of the existence in the diencephalon of special centers for weight loss and obesity.. However, although the dependence of some forms of pathological emaciation and obesity on dysfunctions of the autonomic nervous system is apparently undeniable, the question of the localization of the center of fat metabolism meets the same difficulties, the impossibility of eliminating which prompts to doubt the very possibility of the existence of specific centers of heat, sugar and.

Tennissen, together with Goering, tend to make lipoid metabolism dependent on the center located at the bottom of the third ventricle. Muller believes that the influences predisposing to obesity are directed from the diencephalic center along parasympathetic pathways that play the role of trophic nerves. Dresel, on the basis of literature data, believes that both the deposition of fat and its waste in the body are regulated by the nervous system.. However, the pathways that regulate the deposition of fat in the subcutaneous tissue are still unknown..

Based on the work of Camus and Russi, Laitiel-Levasten seems to be inclined to admit the existence of centers of weight loss and obesity in the gray hillock.. The basis for this assumption is the observation of Camus and Russi that dystrophia adiposo-genitalis syndrome can be caused, like cachexia, by damage to the gray tubercle without dysfunction of the pituitary gland..

On the other hand, there is no doubt that the removal of the cerebral appendage, which is not accompanied by damage to the gray tubercle, can also cause a picture of Frohlich's disease. This question obviously requires further experimental research..

The dependence of obesity (or weight loss) on dysfunction of the endocrine glands is well established.. In particular, obesity can be distinguished due to insufficiency of the intrasecretory activity of the pituitary gland, thyroid gland, and gonads.

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