A recent study by scientists gave them the first insight into how the brain removes waste during restless sleep, highlighting the critical role of norepinephrine, blood flow and cerebrospinal fluid (CSF) in activating the glymphatic system. This system plays a key role in clearing the body of toxic proteins such as amyloid and tau, which are implicated in neurodegenerative diseases such as Alzheimer's disease and which a popular sleeping pill has been shown to negatively affect, Knowridge writes..

U Focus. Technologies has its own Telegram channel. Subscribe so you don't miss the latest and most exciting news from the world of science!

Findings from a study published in the journal Cell highlight the restorative power of sleep, shedding light on its importance for long-term brain health.. During sleep, the brain shifts its attention from processing external stimuli to internal maintenance, such as eliminating waste..

Dr Maiken Nedergaard, co-lead author of the study from the University of Rochester, believes this self-cleansing mechanism may be why sleep has such profound restorative effects.. Study Finds Norepinephrine Organizes Synchronized Slow Waves Known as Microwaves During Non-REM Sleep.

These waves stimulate vasomotion, in which blood vessels rhythmically constrict and promote the movement of CSF through the glymphatic system, effectively flushing out brain waste. Scientists used innovative research methods to study the brains of freely moving mice, marking a departure from previous studies using anesthesia. Advanced techniques, including flow fiber photometry, have provided insight into the natural interaction of norepinephrine and glymphatic activity. According to Natalie Hauglund, lead author of the study, these results bridged a significant gap in understanding the nighttime activity of the organ..

The study also examined the effects of the popular sleeping pill zolpidem, revealing potential risks. Although the drug is effective in inducing sleep, it disrupts the natural fluctuations of norepinephrine, interfering with the functioning of the glymphatic system. This disorder has scientists concerned about long-term use of sleep aids because they may interfere with the brain's clearing process, potentially increasing the risk of neurological disorders.

In addition to understanding the more precise effects of certain medications, the study paves the way for the development of therapies that target norepinephrine dynamics to improve the quality of natural sleep without impairing its restorative functions, the authors said.. This approach could benefit people with sleep disorders by offering solutions that protect brain health and ensure a better night's rest.

Previously, Focus wrote about how brushing your teeth helps identify Alzheimer's disease. Alzheimer's disease has a variety of symptoms, one of which is the decline of motor functions, which can easily manifest themselves in the most mundane activities..

Focus also wrote that you can fight Alzheimer's disease with food. A study has shown that a person with Alzheimer's disease can significantly improve their condition by changing the way they eat..

Important! This article is based on and does not contradict the latest scientific and medical research. The text is for informational purposes only and does not contain medical advice.. To establish a diagnosis, be sure to consult a doctor.